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Atg8 in yeast), and ATG12 inhibits autophagy [55]
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Restoring mannose metabolism enhances T-cell antitumor activity and limits exhaustion by promoting stem-like programs through preserving Tcf7 expression and epigenetic stemness, offering a potential strategy for improving ICT [389]

Mutations in ASH1L disrupt the expression of the NTRK2 gene that encodes the TrkB receptor, leading to impaired neurite outgrowth and synaptic deficits associated with ASD [149]

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