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A systematic review of over 94,000 adults seeking obesity treatment found that 14% had binge eating disorder on clinical interview and up to 26% reported moderate-to-severe binge eating on self-report measures ( Melville et al., Int J Eating Disorders, 2025 )

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Among those 65 and older, use of GLP-1 agonists is somewhat higher for men than for women, researchers wrote

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Notably, CT-388's weight loss curve had not plateaued at 48 weeks, suggesting the final treatment effect could be even higher at 72 weeks in the Phase III program

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93 It is important to distinguish between direct GLP-1 receptor agonists and DPP-4 inhibitors

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