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A systematic review of over 94,000 adults seeking obesity treatment found that 14% had binge eating disorder on clinical interview and up to 26% reported moderate-to-severe binge eating on self-report measures ( Melville et al., Int J Eating Disorders, 2025 )

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Among those 65 and older, use of GLP-1 agonists is somewhat higher for men than for women, researchers wrote
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Notably, CT-388's weight loss curve had not plateaued at 48 weeks, suggesting the final treatment effect could be even higher at 72 weeks in the Phase III program
93 It is important to distinguish between direct GLP-1 receptor agonists and DPP-4 inhibitors
