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brands that ignore it will see their business impacted in small ways and large, and in ways that feel beyond their control.

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Looking Ahead As the market evolves, stakeholders are watching for regulatory updates and court decisions that could reshape the boundaries of compounding

--- Here are some potential actions covered in the article for payers and employers to take as a result of this shift: Update formulary tiers and step therapy policies (consider the impact on comorbidities) Support members transitioning off GLP-1s after reaching their goals Create differentiated access pathways based on patient risk profiles Monitor realworld outcomes beyond A1C (cardiovascular, renal, adherence) Model the downstream impact on generics and legacy therapies --- Commercial plans are accelerating GLP-1 uptake and favoring the simplicity of a single therapy
