how to maintain weight loss after stopping glp 1 GLP-1 effects treatment My GLP-1 Journey: 225 lbs

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Lizzo is an open book about her weight release journey, including how her secret to trimming down involved Ozempic, but it was also a diet change and excercise

Filingeri noted that this research study was designed to further examine changes in weight, body fat mass, and muscle mass in patients taking incretin medications. We found that, under close supervision and regular follow-up from an obesity medicine specialist, patients were able to lose fat mass with only a minimal decline in muscle mass. Alexandra Filingeri, DCN, RCN Filingeri pointed out that the results of this study cannot be generalized to patients receiving medication via telemedicine without routine body composition analysis, nor can they be generalized to in-person visits without utilizing body composition analysis

It is contraindicated in patients with a personal or family history of medullary thyroid cancers (MTC) or patients with multiple endocrine neoplasia syndrome type 2 (MEN2).[30] FUTURE INDICATIONS AND TRIALS Oral semaglutide has been explored with higher doses of 25 and 50 mg in ongoing PIONEER plus trials.[39] Another trial under the name PIONEER TEEN is ongoing to see the efficacy and safety of semaglutide in children and teenagers with age 10 years to 17 years.[40] PIONEER REAL is a global prospective, non-interventional single-arm real-world study with oral semaglutide.[41] EVOKE and EVOKE plus are ongoing trials to see the effect of oral semaglutide in Alzheimers disease.[42] SOUL is an ongoing CV superiority trial with an objective to prove CV benefits with this molecule

But a recent review of the literature by researchers at the University of Virginia raised a flag: they found that while GLP-1 drug therapy clearly reduces body weight and fat, these benefits dont translate into significant improvements in VO2max or overall cardiorespiratory fitness (2)