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Tirzepatide likely works better because it works on two different receptors

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The 10 and 15 mg doses of tirzepatide significantly reduced the number of large triglyceride-rich lipoprotein particles (TRLP), small low-density lipoprotein particles (LDLP), and the LPIR score compared to both the placebo and dulaglutide

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Tani S, Itoh H, Okabayashi Y, et al

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The short answer is: likely yes, with appropriate medical supervision

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Postgraduate Medicine, 134 (1), 1419

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Association between left atrial epicardial fat, left atrial volume, and the severity of atrial fibrillation

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