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It is possible that CFS sufferers have had these "inborn errors of metabolism" for much of their life, without experiencing any significant problem until some precipitating event such as stress or a chronic infection has triggered chemical changes inside the body thereby resulting in CFS

The interplay between ferroptosis and inflammation: therapeutic implications for cerebral ischemia-reperfusion

Determination of reduced glutathione in human plasma by RP-HPLC

DOI: 10.1016/j.cell.2004.05.002 79

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