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2009 RCT documented improvements in mottled hyperpigmentation alongside fine-wrinkle reduction in photoaged skin 10

Eden offers a convenient and comprehensive approach to obtaining these injections

[DOI] [PubMed] [Google Scholar] Hadri KE, Courtalon A, Gauthereau X, Chambaut-Gurin A-M, Pairault J, Fve B

These groups of drugs are GLP-1 and glucagon receptor agonists

(And, of course, its possible to have this type of tear AND the other type at the same time, although I havent come across this yet.) It seems very difficult to get a clear explanation anywhere of how significant these intrasubstance tears are and what constitutes a mild, moderate or severe version of one