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In addition, we found that AAV- Ksp - Usp2 transfection, but not AAV- Ksp - Usp2 K447R, reversed the reduction in renal fibrosis and ferroptosis induced by Usp2 KO in UUO mice (Fig

Non-coding RNA (ncRNA) has a pivotal role in regulating the expression and activity of FSP1 in cancer cells

In contrast, 16.9% of the mitotically dividing cells exhibited anaphase bridges in G3 pot1a mutants

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Sies H, Jones DP (2020) Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

While NPPC-centered therapy holds substantial potential for mitigating IDD, translating this promise into effective clinical treatments requires overcoming major translational challenges