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In the current MASLD era, methotrexate-induced hepatotoxicity must be understood in the context of host metabolic dysfunction, obesity, diabetes, and alcohol use that amplify oxidative and inflammatory liver injury
However, smokers are generally advised to avoid beta-carotene and any supplements that contain it
Co-encapsulation of synthetic drugs and natural bioactive chemicals within the same PLGA nanoparticle system could have a synergetic therapeutic effect
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