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doi: 10.1177/1559827609335350 17
[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Schucht P, Raineteau O, Schwab OE, Fouad K

Others deal with severe pain that lasts the entire day, disrupts sleep, and interferes with daily activities
These two proteins form the structural backbone of firm, elastic skin, and their decline is a major reason skin goes slack after shedding weight

It has not been approved by the FDA for obesity, diabetes, or any other medical indication

The biological rationale is that the body's healing program is itself coordinated, so supporting cell migration and local repair signaling together, rather than in isolation, is intended to better match how tissue actually rebuilds
