glutathione is most abundant antioxidant in the body Participation Prevention of Cardiovascular Diseases 9 Health Benefits of Glutathione

80 These effects impede the re-fusion of impaired and normal mitochondria, separating damaged mitochondria for subsequent incorporation into autophagosomes, 80 which then fuse with lysosomes to degrade damaged mitochondria

In Crohns disease, for example, where oxidative stress leads to mucosal layer damage, glutathione peroxidase (GPx) activity is increased during the active phase and returns to normal during remission [25]

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TBI mice exhibited impaired spatial learning compared to sham controls, manifesting as altered swimming paths

10.1172/JCI69000 12 BarcaE.MusumeciO.MontagneseF.MarinoS.GranataF.NunnariD.et al

RubeoCGiordanoMTannousMDurnAMComitSLandolfiVet al