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Exploring the association between obesity and cerebral inflammation after stroke, obese mice fed a high-fat (60%) diet showed larger post-stroke infarct volumes and increased chemokine expression (CXCL-1 and CCL3), blood-brain barrier (BBB) permeability, and neutrophil and microglia counts [86]

Kosower NS, Kosower EM

NB and LK contributed to the data interpretation

(apologies for any medical errors in crafting this message just a layperson trying to get to the bottom of this issue Thanks- Mary Does low folate and B12 also cause low homocysteine

Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N -Acetylcysteine) Supplementation

All of these may be things you chalk up to getting older, but that would be an incorrect assumption