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These findings suggest a dual mechanism enhancing fatty acid catabolism while reducing oxidative stress

Taken together, these results strongly suggest that L-carnitine supplementation attenuates lenvatinib-induced muscle toxicity

In 2023, a clinical trial (N = 90 LOE 3a) with daily supplementation of 3 g LC in the experimental group and equivalent placebo in the control group was conducted

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With more L-carnitine in the muscle, the amount of acetyl-CoA production from -oxidation may increase, leading to more citrate being produced