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Brain tissue apoptosis and necrosis are caused by insufficient blood supply and a lack of oxygen [132,133,134]

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[19] During the initial titration phase for subcutaneous semaglutide (Ozempic), the starting dose of 0.25 mg once weekly for the first 4 weeks is primarily for acclimation to minimize gastrointestinal side effects, with very little to no significant weight loss expected (typically 03 pounds or ~02% of body weight, mainly from reduced appetite and possible water weight)

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