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Together, these systems show how genetics and hormones can shape metabolism, appetite, and weight management in different ways for different people

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The main autophagy inducers are starvation and lack of growth factors which, through inhibition of mammalian target of rapamycin (mTOR) signaling, then trigger ULK1 complex (ULK1-ATG13-FIP200-ATG101) formation at Atg9-containing membranes and activation of the class 3 phosphatidylinositol-3-OH kinase (PI(3)K) complex (Jung et al., 2010)

Glutamate transporters: Taking up glutamate from the synapse Glutamate transporters regulate how much glutamate is available in the synapse, thereby controlling the level of extracellular glutamate that can activate nearby neurons

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