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Structural modeling and 500-ns molecular dynamics simulations revealed that G18 binds within the ATPase domain, forming stable hydrogen-bonding and hydrophobic interactions that stabilize the enzyme-inhibitor complex

Lactation [see Use in Specific Populations (8.2)] Advise female patients not to breastfeed during treatment with JUXTAPID

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Variants of this gene can affect the activity of the GPx-1 enzyme

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[DOI] [PMC free article] [PubMed] [Google Scholar] 386.Talati M., Meyrick B., Peebles R.S., Davies S.S., Dworski R., Mernaugh R., Mitchell D., Boothby M., Roberts L.J., Sheller J.R