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Trichobilharzia regenti , a pathogen of the avian and mammalian central nervous systems

and an anti-stress effect

Brain metabolites are secreted and infiltrated into CSF to regulate the entire central nervous system and even organs throughout the entire body ( Recent research suggests that there is a class of neurons in contact with CSF on the ependyma called CSF-contacting neurons (CSF-cNs), and the location of CSF-cNs and ciliary morphology suggests that they sense physical and chemical signals in the CSF (Orts-DelImmagine and Wyart, 2017)

These converging mechanisms create a cocktail effect, producing cumulative reproductive toxicity that exceeds the effect of any single pollutant

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