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2 Pathogenesis of pulmonary fibrosis Tissue repair following injury is an inherent biological mechanism that restores tissue integrity through the organized replacement of damaged or deceased cells (Figure 1: the initial sustained injury phase, the inflammatory cell migration phase, the fibroblast migration/proliferation/activation phase and finally, the excessive deposition of ECM and fibrosis phase

Green-synthesized MSNs using the plant polyphenols or chitosan further enhance additional selectivity against less cytotoxic parasites in mammalian cells [279]

However, each member of the GPX family has a different mechanism of action and site of action in maintaining redox balance

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