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While considered reliable and straightforward, most of the experimental assays are labor intensive and are impractical to implement with a large number of mAb candidates

R., Lukens, J
Strong chemistry, manufacturing, and controls practices encompass design, production, and quality assurance measures that ensure translational reliability

A possible explanation may be the large inter-individual difference in biliary B 12 excretion

165 Vitamin B 6 is widely available in foods and severe deficiency is rare
