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The mechanisms by which Tbx1 mutation affects brain development and brain function are unknown, but they are non-cell-autonomous mechanisms (37) because in the mouse brain, Tbx1 expression is limited to brain vessels, and it is not expressed in neurons or other brain cell types (2, 38) ( Moreover, not all brain ECs express Tbx1

Biochemical properties

This represents roughly 6% of the human genome

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Cerebrolysin loading 20-30mL 5 days weekly for 4 weeks then 10mL quarterly maintenance

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