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Weinstock LB, et al

For an acute injury, users often report effects within the first cycle, and inflammatory markers like hs-CRP may shift within the first few weeks.

In our own studies we found that the FGF-2 mRNA expression began to increase already from the first weeks of cuprizone feeding and was even stronger up-regulated after 4 weeks (severe demyelination) corresponding to the intensive proliferation of OPC (Gudi et al., 2011)