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[DOI] [PubMed] [Google Scholar] Schlaeppi K., Bodenhausen N., Buchala A., Mauch F., Reymond P

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Its anabolic and growth-promoting effects are largely indirect, primarily via stimulation of hepatic IGF-1 production, whilst its direct metabolic effects, particularly those related to lipid metabolism and adipose tissue regulation, are believed to be mediated by specific domains within the GH molecule itself