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Some therapeutic mAbs (including trastuzumab) do not harbor this allotype, which could partially explain differences in immunogenicity across different mAb drugs (78, 79)
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It reveals microbiota-metabolite-host interactions, advancing microbiome-based therapies for neurological disorders
In summary, breastfeeding confers protection not through a single pathway but through a synergistic interaction of barrier enhancement, microbiome shaping, immune education, and antigenic delay, highlighting its critical role as a modifiable factor in the primary prevention of type 1 diabetes
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