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Discussion Here we investigated the contribution of the TSS pathway to the antioxidant and ferroptosis stress regulation in SCD erythroblasts

The main focus is to provide new strategies and recommendations for interventions targeting these mechanisms, as well as for personalized treatment approaches, combination therapies, and the development of innovative drug therapies

Consequently, dysregulation of GSH production is seen in a number of medical conditions, such as renal failure 20 , liver injury 21 , diabetes, neurological diseases 22 , organ fibrosis 23 , and cardiovascular disease 24

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