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Recent studies have shown that the ability of cells to generate mitochondrial supercopmplexes enhances exercise endurance and, at least in mice, results in suppression of cellular senescence, a key characteristic of aging cells

39 YeL.HuangY.ZhaoL.LiY.SunL.ZhouY.et al (2013)

Customers who choose our recovery IVs often feel more run-down or depleted than usual, so they may notice changes more quickly simply because their baseline comfort or energy levels are lower

Heat production from uncoupling electron transport would be another- this is thought to lead to death before ATP depletion
Direct injection avoids any concern about absorption through tissue, and most of the foundational research on these peptides was conducted using injectable administration, so theres a long history of use this way

Ozone helps increase high-density lipoprotein (it has an anti-inflammatory action), and reduces some inflammatory compounds, such as C-reactive protein, total cholesterol, low-density lipoprotein, triglycerides, and homocysteine. An additional effect of the therapy may be a regulation of the autonomic nervous system in complex regional pain disorders. Presenters at multiple ozone conferences have reported improvement in both local and diffuse pain disorders with simple intravenous ozone applications
