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A growing number of studies suggest that ferroptosis plays an important role in the pathogenesis of various types of liver disease, including hemochromatosis, alcohol-associated liver disease (ALD), hepatitis C virus (HCV) infection, non-alcoholic steatohepatitis (NASH), and hepatocellular carcinoma (HCC) [9, 10]

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The complex role of Wnt ligands in type 2 diabetes mellitus and related complications

For HNE induction, the activation of the critical AP-1 binding elements in both human GCL genes can is achieved through the Jun N-terminal kinase (JNK) pathway (Dickinson et al., 2002)