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A trial involving an anti-CD40L antibody, Ruplizumab, was halted due to severe thromboembolic events

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Carcinogenesis 29 , 12351243 (2008)

[DOI] [PubMed] [Google Scholar] 26.Rai R, Saraswat VA, Dhiman RK

They proposed that for the DR23 ions to reach the adsorption sites, they must first (at least partially) exit the hydration shell, which necessitates energy input

Dose, age, body mass index (BMI), and baseline SBP may also impact the magnitude of these effects
