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These pathological processes are closely associated with AS, cerebral small vessel disease, and bloodbrain barrier (BBB) dysfunction, positioning VaMCI as an important disease model for investigating cerebrovascularneural interactions
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Metabolic diseases A group of diseases characterized by disrupted metabolism that adversely affect normal cellular function and structure

It affects approximately 50% of men by age 50 and a significant proportion of women

These peptides activate MRGPRX2, a mast-cell receptor that fires on positively charged, aromatic molecules and releases histamine into the tissue. Sodium and chloride ions screen the peptides positive charge, so the receptor sees less of it and the welt shrinks
