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Perhaps the abrupt increase in fat intake augmented dopamine depletion and/or oxidative stress in the substantia nigra (163)

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Even though the clinical diagnosis of CD affects adherence to the GFD, data suggest that around one percent of the general population is affected by this condition

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As from previous studies, isolated human cardiomyocytes express PDE5 similarly to human endothelial cells and human peripheral blood mononuclear cells (59)