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Acetyl L-Carnitine is the acetylated form of l-carnitine which is readily utilized in the Krebs Cycle (i.e., by the liver and other tissues.) The acetyl group of acetyl l-carnitine is used to form acetyl-CoA, the most important intermediary in the generation of energy from amino acids, carbohydrates and fats, and has been shown to lower triglycerides.

Using knockouts and also overexpression of selected genes, we could observe that many of the upregulated genes were involved in the cellular response to 5-OP accumulation