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This observation is supported by clinical studies showing that chronic stress and dysregulation of the stress response were found to contribute to the maintenance and propagation of various CSCs in patients suffering from chronic stress, anxiety, depression, and suicidal behaviour [226, 251, 252]

Neuroendocrinol Lett Mutter J, Curth A, Naumann J, Deth R, Walach H (2010) Does inorganic mercury play a role in Alzheimers disease

doi: 10.1159/000489241

Furthermore, research has shown it activates interferon-gamma production in T-cells, which is crucial for immune defense

KRAS-mediated signalling plays an important role in the formation of an immunosuppressive TME and the modification of immune cells (Fig

doi: 10.1101/gr.128876.111