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Antioxidants Significantly Affect the Formation of Different Classes of Isoprostanes and Neuroprostanes in Rat Cerebral Synaptosomes

Supports antioxidant & inflammatory - modulating activity

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However, the concentrations of these conjugates are significantly higher in the substantia nigra of the PD patients, suggesting that these compounds may contribute to the damage in this region of the brain in PD patients (Spencer et al., 1998)

[44] Similarly, genetic variations in iron transporter genes known to increase serum iron levels also reduce lifespan and the average number of years spent in good health

Saba R, Alsayed A, Zacny JP, Dudek AZ