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Treatment effect appears to be clinically evident starting from one to three months after treatment completion, with a subsequent progressive decrease of the achieved EF benefit over time, although some effects could be still detected up to five years after treatment [490,492,498]

38 Absent dose-limiting adverse effects, ALCAR, and ALA were increased to 1000 mg twice daily and 600 mg twice daily, respectively, at week 1 and to 1000 and 600 mg 3 times daily, respectively, at week 2

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3,16,205 The combination of intrauterine insemination with ovulation-inducing drugs also may be used in the setting of male infertility due to low sperm counts