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Although GSTs are generally viewed as playing a protective role in foreign compound metabolism, they can also catalyze reactions that lead to toxification

2.Glutathion synthesis The first step of GSH synthesis is rate-limiting and catalyzed by glutamate-cysteine ligase (GCL) formerly referred to as -glutamylcysteine synthetase (GCS)

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Data availability Plasmids described in this study were deposited to the Addgene repository under accession numbers 257812257815

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