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Description

Optimal functioning of mitochondria is dependent on normal levels of carnitine

Carnitine is responsible for the movement of longchain fatty acids (FAs) into the mitochondria for oxidation through the action of carnitine palmitoyltransferase1 (CPT1) (Longo et al., 2016)

These findings highlight that choline deficiency may become more severe in certain populations, such as postmenopausal women

How L-Carnitine Works in Fat Metabolism L-carnitine functions as a shuttle molecule that transports long-chain fatty acids into mitochondria, the cellular powerhouses where fat oxidation occurs

Flum, DR Gastric bypass surgery vs intensive lifestyle and medical intervention for type 2 diabetes: the CROSSROADS randomised controlled trial Diabetologia 59 5: 945-53