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In line with these findings, bortezomib, alone or in combination with chloroquine, increased NOS I expression, while chloroquine did not alter the expression of any NOS isoform (Fig

The kynurenine quinolinic acid can act as an excitotoxin: levels increase following ischemia, and correlate with increased neurodegeneration (Saito et al., 1993)

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The mechanism of action of sodium pentobarbital is mainly through the potentiation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system, which produces anesthetic effects

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