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Stable Over Time: Preserves activity for long-term research use

Somatic mutations known to cause MDS are mutations in epigenetic regulators, (TET2, DNMT3A, ASXL1, EZH2), RNA spliceosome components (SF3B1, SRSF2, U2AF1), transcription factors (RUNX1, TP53), signal transduction pathways (KRAS, NRAS, JAK2), and the cohesion complex (SMC3, SMC1A, RAD21, STAG2) (39, 40)

This study also noted side effects of the KD: five individuals on the KD experienced GI disturbances, compared to two patients in the control group who reported similar symptoms

CrossRef Surgical Extent of Low-to-Intermediate Thyroid Cancer: Molecular Testing and Clinical Decision-Making Jae Won Chang International Journal of Thyroidology.2025