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The facial cream is given in the same 5 mg/mL (0.05%) doses

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It also helps to understand why the three arms were combined in the first place

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Modern studies indicate that licorice can inhibit the intestinal absorption of diester diterpene alkaloids from Aconitum species and promote their metabolism and excretion through the induction or regulation of drug-metabolizing enzymes and efflux transporters, thereby mitigating toxicity [39]