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FIGURE 3 Due to lack of oxygen, hypoxia leads to inhibition of prolyl hydroxylase, which is also referred as prolyl hydroxylase domain (PHD) protein

6) Resting Time: Once the steak reaches your desired level of doneness, remove it from the oven and let it rest for a few minutes before serving

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There is no human clinical data establishing a timeline for gut-specific effects

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Loading phase (deficiency): 1000 mcg IM or subQ daily or every other day for 1 to 2 weeks Maintenance: 1000 mcg monthly is a standard maintenance dose for conditions like pernicious anemia Wellness protocols: may use lower doses weekly, though this is less established clinically In ml: cyanocobalamin is typically supplied at 1000 mcg/ml, so a 1000 mcg dose equals 1 ml