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However, in a recent study in 106 patients with alcohol use disorder with variable degrees of liver disease, intestinal permeability normalized after a 3-week detoxification program, while markers of bacterial translocation (LBP) remained elevated (149)

The break is not required for safety or receptor resensitization, but it allows for reassessment and prevents indefinite use of a compound with limited long-term human data

When recent alcohol use could violate program terms, ETG provides a far more useful window than methods focused only on active intoxication

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Lyman M, Lloyd DG, Ji X, Vizcaychipi MP, Ma D
