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Additionally, ROS acts as secondary messengers in intracellular signaling cascades, modulating cellular processes such as antioxidant gene regulation, cell proliferation and survival, and autophagy [249,250,251]

Previously, studies have investigated and found siderophores and heme iron receptors as promising candidates for antigens as part of a vaccine formulation [258,259]

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Les scientifiques explorent activement des moyens d' augmenter naturellement la production de glutathion

Stroke models showed that 1 mg/kg erinacine A administered to rats increased cell survival and reduced infarct volume after cerebral ischemia [8]

Since no definite TAAs have been identified in Hepa1-6 cell line, here we intend to use 7 neoantigens with strong immunogenicity that we have previously identified in Hepa1-6 cell line to evaluate neoantigen-specific immune response induced by poly(I:C) plus RT (Chen et al, 2022)