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As collagen levels drop, the skin's supportive scaffold, called the extracellular matrix, gets thinner and weaker, showing up as visible fine lines, wrinkles, sagging, and loss of elasticity in the skin

Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy

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Therefore, it is possible that this result may reflect PMS

Raskin I, Ribnicky DM, Komarnytsky S, Ilic N, Poulev A, Borisjuk N, et al