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Conclusion In patients with PD and OFF episodes, APL demonstrated lower C max and relative bioavailability but similar exposures (AUCs) versus SC apomorphine within the approved dose range
This interaction blocks p53-mediated apoptosis, allowing senescent cells to survive.57 FOXO4-DRI, a synthetic peptide, disrupts the FOXO4-p53 interaction, reactivating apoptosis and clearing senescent cells
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Then repeat
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