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When that framework is missing, even the best-researched combination can underperform or create unnecessary frustration

Anti-CD38 antibodies are transforming MM treatment owing to their profound anti-myeloma activity as single agents and in combinations, as well as their manageable safety profiles [5]

And the nagging joint pain hasnt budged despite optimized T levels

They also release endorphins in a number of patients, which gives an overall analgesic effect

Melzig MF, Funke I
