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A two-sided p-value below 0.05 was considered statistically significant

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HPCAL1 is a neuronal calcium sensor that has recently been identified as an autophagy receptor that induces ferroptosis

Amplitudes of b- and d-waves were measured as means within fixed, characteristic time intervals (pre-stimulus baselines set to 0), which were selected to include b-wave or d-wave peaks for consistent measurements of response amplitude

Disrupted iron metabolism, particularly iron accumulation in joint tissues, contributes to oxidative damage and inflammation, suggesting a potential link to disease progression