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However, these adducts have been found to be formed at a considerably slower pace (24 h at 100 o C) than the glutathione reaction, suggesting that glutathione conjugation takes place in vivo before it can react with DNA (Portoghese et al., 1989)

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Further studies that more precisely delineate the role of MRP1 in the actions of this important chemical messenger are eagerly anticipated

In adult tissues, this pathway has been implicated in regeneration and wound healing (Chmielowiec et al., 2007

10.1016/j.nbd.2021.105470 35 GaoH.-M.ZhouH.ZhangF.WilsonB