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Because Epithalon is modelled on a pineal-derived peptide, a strand of research examines its influence on the pineal gland's regulation of melatonin secretion and circadian (sleep-wake) rhythm in animal models

These ADAs can neutralize the therapeutic efficacy, alter pharmacokinetics, and even cause adverse immune responses

10.1046/j.1365-2133.1998.02511.x

But that doesnt mean you wont notice changes

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