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Disruption of the epithelial barrier can 1) affect efficient nutrient absorption, 2) facilitate pathogen translocation into the bloodstream and cause systemic inflammation, and 3) alter gut microbiota composition [1]

doi: 10.1007/s00253-021-11114-3 85 DemonchyJ.BiardL.Clere-JehlR.WalletF.MokartD.MoreauA

Zhang et al., 2008)

Tsentemeidou A, Sotiriou E, Sideris N, Bakirtzi K, Papadimitriou I, Lallas A, Ioannides D, Vakirlis E (2022) Apremilast in psoriasis patients with serious comorbidities: a case series and systematic review of literature

Amphibians are also very sensitive to low pH because of their sensitive skin

Contraception 65: 305-311