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References American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5)

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Luteolin suppresses this pathway by preventing phosphorylation and degradation of the inhibitory protein IB, thereby blocking nuclear translocation of NF-B p65 and reducing transcription of pro-inflammatory cytokines (TNF-, IL-1, IL-6), iNOS, COX-2, and adhesion molecules (Khan et al., 2024)

While the exact incidence of phototoxic reactions is unknown, clinicians should be aware of the relative abundance of such reactions, particularly as outdoor leisure activities increase and as the long-term correlation for cutaneous tumor development continues to rise [228]