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2022 May;36(5):451-482

Some studies show a skin-lightening benefit as well, due to direct and indirect inhibition of the tyrosinase enzyme and switching from eumelanin to phaeomelanin production

These enhanced formulations also add the cost of the enhancer itself, though cyclodextrins are relatively inexpensive

Hormone testing is helpful-- especially for pituitary functions that affect stress hormones, sex hormones, fluid balance, and prolactin release ("post-traumatic stalk syndrome")-- and additional labs can further help identify the extent and severity of neural injury as well as the potential for progression to cognitive impairment or dementia (including tests such as phosphorylated tau protein, neuron-specific enolase, 14-3-3 protein, neurofilament light-chain, amyloid 42/40 ratio, GFAP, ApoE4, etc.)

Clin Biochem (2013) 46:30812

IGF-1R: IGF-1 receptor
